Minoxidil Powder

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Autor : Jack
Updatezeit : 2022-08-19 16:34:44


Product Data Sheet

INCI Name (US): Minoxidil
INCI Name (EU): Minoxidil

CAS #: 38304-91-5

General Information/ Characteristics:

Minoxidil solution and foam are used to help hair growth in the treatment of male pattern baldness. It is not used for baldness at the front of the scalp or receding hairline in men. The foam and 2 % Minoxidil solution is also used to help hair growth in women with thinning hair.

Minoxidil is the only treatment for Male and female patterned (AGA) hair loss that has been approved by FDA.

Benefits / Application: Benefits:

  1. Reversers the hair loss process and help hair re-growth
  2. Works on crown of the scalp.
  3. Protect and nourishes hair during natural seasonal hair shedding
  4. Stable and easy to implement in the formulations. Safe and Effective for both Men and Women.
  1. Hair tonic
  2. Hair lotion
  3. Hair ampoules
  4. Hair Cream
  5. Hair Foam
Formulations Advices: Dosage: 2% for women; 5% for men.
Regulatory Status: No applicable

Physic-Chemical Properties:

Appearance Color
Loss on drying
Crystalline Powder White to off-white Max. 0.5%

Physic-Chemical Properties (Cont.):

Melting point Solubility

(by IR Absorption spectrum)
Assay by HPLC (on dried basis)
Impurities: Residue on ignition Heavy Metals
Organic impurities by HPLC
Residual solvents by GC-HS:
Methanol Piperidine
248 - 268ºC
Soluble in alcohol and in propylene glycol, sparingly soluble in methanol, slightly soluble in water.
Practically insoluble in chloroform, in acetone, in ethyl acetate and in hexane.
In Accordance with IR absorption spectrum of Minoxidil working standard.

Min. 97.0% - Max. 103.0%
Max. 0.5%
Max. 20 ppm
Total impurities: Max. 1.5%
Max. 3000 ppm
Max. 1000 ppm
*These values indicate typical specification; they are not intended to be used as product specifications
Additives: Preservatives: No applicable

Product Description

In recent years, with the continuous improvement of living standards, more and more people have begun to realize the importance of personal image. And the hair that occupies the commanding heights in the overall image naturally cannot be ignored. As an important part of human beauty, hair shoulders the important task of showing the beautiful overall image of human beings.

However, in modern life, baldness and hair loss have become a common and frequently-occurring disease in today's human beings, and it is a more sensitive and miserable thing. According to the American Academy of Facial Plastic and Reconstructive Surgery, due to the fast-paced work and life, more than two-thirds of men and more than one-fifth of women in the world are suffering from baldness and hair loss, which affects normal life and work. One of the factors that most bald and alopecia sufferers look to with medication to make up for their lack of image. The factors that cause baldness or hair loss are divided into two types: congenital and acquired. Congenital alopecia or alopecia are mostly autosomal recessive or dominant inheritance. Acquired baldness is often caused by diseases (such as inflammation, infection, endocrine disorders, etc.), nervous system disorders, mental disorders, nutritional and metabolic disorders, injuries, scars, and chemical factors. Then came minoxidil, a vasodilator that can be used to treat hair loss.


Minoxidil is a peripheral vasodilator used in the treatment of severe, resistant hypertension with rapid onset and long-lasting effect. In long-term clinical application, it is found that patients who take the drug for more than one month can have hirsutism of different degrees, so that people have carried out extensive and in-depth research on its use in the treatment of baldness and hair loss. Its vasodilating effect can improve the blood circulation and nutrient supply of the scalp, and make the hair follicles re-grow. It is suitable for baldness and hair loss caused by various reasons.

The results of the study show that the spray made of a solution of minoxidil 1% to 10% (10mg/ml to 100mg/ml) has a total effective rate of 63% in the treatment of baldness (baldness), and there are always The efficiency is 100%, and it has no irritating and allergic reactions to intact skin, no obvious toxic reactions to systemic administration, and no carcinogenic and teratogenic effects through skin absorption, indicating that this product is a safe and effective alopecia, Hair loss treatment medicine, and easy to transport, store, carry and use.

Side Effects

Adverse reactions to minoxidil use mainly occur on the skin, with the most common symptoms being scalp itching, scaling, and hirsutism. Contact dermatitis can also occur with increased use.

Currently, oral minoxidil (OM) has not been used to treat hair loss due to potential side effects at doses of 10-40 mg per day. Sodium and fluid retention were the most prominent adverse effects, especially in patients with renal disease, and were usually manifested as edema or weight gain. Coadministration with beta-blockers usually reduces sodium/fluid retention and controls heart rate. Drug-related cardiac conditions include, most commonly, reflex tachycardia and, less commonly, ECG changes in patients with end-stage renal disease, pericardial effusion, and congestive heart failure.

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